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  • Title: [Effect of bromocriptine on 3H-dopamine uptake in hypothalamic synaptosomes of intact and adrenalectomized rats].
    Author: Iatsyk MI.
    Journal: Vopr Med Khim; 1986; 32(5):60-2. PubMed ID: 3776119.
    Abstract:
    Intensity of 3H-dopamine uptake in hypothalamic synaptosomes was similar both in intact rats and in the animals which received a single administration of bromocriptine at a dose of 5 mg/kg within 4 hrs. Within 4 days after the drug administration incorporation of the label was increased 1.22-fold and 1.28-fold in intact and adrenalectomized rats, respectively. Alterations in dopamine uptake in hypothalamic synaptosomes caused by bromocriptine appear to be one of dopaminergic-dependent effects of the drug in the animal brain structures.
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