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  • Title: [Temperature effects at the NADP+ and NAD+ levels in the mycelium of P. nigricans Thom. strains grown on different carbon sources].
    Author: Rogal' IG.
    Journal: Antibiotiki; 1979 Jul; 24(7):483-7. PubMed ID: 37800.
    Abstract:
    The effect of elevated temperature of the medium on the levels of NADP+ and NAD+ in the mycelium of highly productive strain 117 and low productive strain B of P. nigricans Thom was studied at various developmental periods on the mineral medium in the presence of glucose, succinate or acetate. It was found that in the presence of glucose the elevated temperature markedly stimulated the initial growth of the culture, decreased the level of NADP+ in strain 117 by the 48th hour and increased the level of NAD+ in both the strains. At later periods it decreased the rate of the dinucleotide accumulation during the culture development. With the use of succinate under these conditions the levels of NADP+ in both the strains during the growth phase (the 2nd and 5th days) and by the 9th day markedly increased, while the NAD+ concentration increased only by the 2nd day in both the strains and by the 9th day in strain B. When the strains were grown in the presence of acetate, the elevated temperature especially affected the level of NAD+.
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