These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effectiveness of nitrosomethylurea derivatives in the combined chemotherapy of experimental tumors].
    Author: Krutova TV, Ostrovskaia LA.
    Journal: Eksp Onkol; 1986; 8(5):47-50. PubMed ID: 3780511.
    Abstract:
    An antitumour activity of combined application of two nitrosomethylurea derivatives--dimethylnitrosourea and ADEKO with cytostatics of various groups was studied in transplanted tumours of La and L 1210 leukemias and Lewis lung carcinoma. A combined treatment by ADEKO with cyclophosphamide, methotrexate and dibunol resulted in therapeutic synergism evaluated by the tumour growth inhibition activity (kappa *) and by life span (delta tau) increase of tumour-bearing animals. An additive antitumour effect was established in case of a combined application of ADEKO with ftorafur, vincristine, prednisolone and dimethylnitrosourea with methotrexate.
    [Abstract] [Full Text] [Related] [New Search]