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  • Title: Molecular investigations of camelpox virus circulating in dromedary camel population in Rajasthan, India.
    Author: Ranjan R, Marwaha S, Singh M, Narnaware SD, Ranjan A, Sahoo A.
    Journal: Comp Immunol Microbiol Infect Dis; 2023 Nov; 102():102073. PubMed ID: 37826888.
    Abstract:
    Camelpox is an important viral disease of dromedary camel in Rajasthan, India. In the present study, partial C18L gene sequences (n = 6) of camelpox virus (CMLV) obtained in an outbreak in Bikaner, Rajasthan, India in year 2022 were compared with other similar sequences obtained in the past in similar geographical location. Clinical and epidemiological features of the disease were also compared. Genomic study suggested variations in C18L gene sequences obtained in the present outbreak from those obtained during the past outbreaks. CMLV were genetically different from cowpox viruses, but appeared identical to CMLV causing disease in Israel, Egypt and Kazakhstan. Genomes of CMLV virus circulating in dromedary camel population of Rajasthan, India appeared diverse and changing, hence complete genome sequencing and identification of genomic changes altering infectivity and pathogenicity is warranted for designing control strategies.
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