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  • Title: Staphylococcus epidermidis ventriculitis treated with vancomycin and rifampin.
    Author: Osborn JS, Sharp S, Hanson EJ, MacGee E, Brewer JH.
    Journal: Neurosurgery; 1986 Nov; 19(5):824-7. PubMed ID: 3785634.
    Abstract:
    Two cases of ventriculitis with Staphylococcus epidermidis that failed on therapy with an antistaphylococcal penicillin are presented. Both infections responded to a combination of intravenous and intraventricular vancomycin and rifampin. Vancomycin and rifampin represent an important antibiotic regimen for the management of resistant infections of the central nervous system, especially with those due to S. epidermidis or methicillin-resistant Staphylococcus aureus.
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