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  • Title: Asymptomatic CMV infection at birth following maternal primary infection despite valacyclovir treatment and a subsequent negative amniocentesis. Case report.
    Author: Toti MS, Zammarchi L, Pasquini L, Campolmi I, Modi G, Borchi B, Bartoloni A, Trotta M, Galli L, Bernardini R.
    Journal: Eur J Obstet Gynecol Reprod Biol; 2023 Dec; 291():128-130. PubMed ID: 37871349.
    Abstract:
    Valacyclovir is currently the only pharmacological intervention demonstrated to reduce the risk of vertical CMV congenital infection within a randomized clinical trial in case of primary infection during pregnancy. So far, no data are available on the prognosis of children with congenital CMV infection diagnosed at birth after a negative amniocentesis whose mother were treated with valacyclovir during pregnancy, therefore it is essential to carry out a rigorous neurocognitive follow-up in these children in order to investigate the potential clinical consequence.
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