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  • Title: Desmoid fibroma simulating malignant breast neoplasm: A case report and literature review.
    Author: Valente MSVS, Mota FAX, Ricciardi BB, de Carvalho Borges BM, de Lucena Feitosa ES, de Aquino PL, Valente PV.
    Journal: Breast Dis; 2023; 42(1):319-323. PubMed ID: 37899051.
    Abstract:
    INTRODUCTION: Desmoid fibroma (DF) is a disorder characterized by strong clonal proliferation of myofibroblasts and fibroblasts. We describe a case of DF that mimicked a breast tumor, along with a review of the literature on the clinical manifestation, diagnostic process, and course of therapy for this combative disease. CASE REPORT: A 34-year-old female patient with breast lump at the junction of the upper quadrants of the left breast. After the diagnosis of DF, it was decided to perform a sectorectomy of the left breast associated with post-quadrant reconstruction, with immunohistochemistry and findings compatible with DF. DISCUSSION: Clinically manifests as a solid mass that is often painless and occasionally adherent to the chest wall. A treatment strategy should be idealized for each patient. Thus, there is the possibility of performing radical surgery for resection and/or radiotherapy, and surgery may be followed by radiotherapy.
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