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  • Title: Nerve growth factor effect on adenosine transport in cultured chromaffin cells.
    Author: Torres M, Bader MF, Aunis D, Miras-Portugal MT.
    Journal: J Neurochem; 1987 Jan; 48(1):233-5. PubMed ID: 3794704.
    Abstract:
    Chromaffin cells both recently isolated or in culture present a high-affinity adenosine transporter with a Km value of 1 microM. When cells were exposed to nerve growth factor (NGF; 10 ng/ml), the adenosine transporter affinity decreased to 3 microM. This value was maintained from 3 days after plating to the end of the culture period. A change in the transport capacity was observed, with a significant increase (approximately 200-260%) in NGF-cultured cells throughout the period studied.
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