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  • Title: Cistadesertosides B-E, Four New Diastereomeric Lignan Glycosides from the Stems of Cultural Cistanche deserticola in Tarim Desert.
    Author: Nan ZD, Zhu YD, Deng CF, Yang JL, Ma XL, Jiang ZB, Jiang Y, Tu P.
    Journal: Chem Biodivers; 2023 Dec; 20(12):e202301600. PubMed ID: 37963833.
    Abstract:
    Four previously undescribed diastereomeric lignan glycosides, namely cistadesertosides B-E (1-4) were isolated from the stems of cultural Cistanche deserticola in Tarim desert. The structures of these compounds were elucidated on the basis of extensive spectroscopic analyses, including IR, HR-ESI-MS, 1D and 2D NMR, circular dichroism (CD) data and chemical degradation. The in vitro anti-inflammatory activity of the isolates was also investigated. It showed that compounds 3 and 4 exhibited potential effects with IC50 values of 21.17 μM and 26.97 μM, respectively (positive control quercetin, IC50 , 10.01 μM).
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