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  • Title: Acetylcholine receptor antibody in patients with myasthenia gravis.
    Author: Xu XH, Zhu LP, Wu JY, Zhang SZ, Yang GZ, Ba T, Tan MX, Liu SL.
    Journal: Asian Pac J Allergy Immunol; 1986 Dec; 4(2):101-5. PubMed ID: 3801096.
    Abstract:
    The determination of acetylcholine receptor antibody (AChR Ab) titer by an enzyme-linked immunosorbent assay (ELISA) in patients with myasthenia gravis was introduced. The optimal conditions were determined by chequerboard determination. The specificity was confirmed by inhibition tests. The sensitivity is 9 p mole. The comparison of AChR Ab titers among 49 myasthenic patients, 19 non-myasthenic neurological patients and 20 healthy blood donors has shown that it is a highly sensitive, specific, reproducible, rapid, simple and inexpensive method for determining AChR Ab and that it is highly valuable for the diagnosis of myasthenia gravis.
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