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  • Title: [Selective mechanisms of hormonal therapy].
    Author: Stoll BA.
    Journal: Vopr Onkol; 1979; 25(5):67-75. PubMed ID: 380153.
    Abstract:
    Recent studies concerned the origin and treatment of mammary gland cancer are reviewed, with special attention to mechanisms of hormonal therapy. The comparative roles of prolactin and estrogens in originating mammary gland cancer and the relationship between activity of sex hormones and the presence of special target receptors are described. The role of estrogen receptors depending on their sensitivity to hormones is stressed, and several possible mechanisms of hormonal sensitivity are pointed out. Different mechanisms of originating mammary gland cancer and hormonal methods for cancer treatment are discussed. The focus is placed on understanding hormonal antagonism, cell metabolism and immunological reactions for this kind of cancer. The role of emotional stress in the pathogenesis and treatment of cancer is touched upon.
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