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  • Title: Basically substituted ellipticine analogues as potential antitumor agents.
    Author: Werbel LM, Angelo M, Fry DW, Worth DF.
    Journal: J Med Chem; 1986 Jul; 29(7):1321-2. PubMed ID: 3806584.
    Abstract:
    Installation of a basic side chain on the ring nitrogen of ellipticine did, as expected, improve the DNA binding properties of these molecules as measured by an ethidium displacement assay. In vivo antitumor activity was not, however, improved.
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