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  • Title: SleepSIM: Conditional GAN-based non-REM sleep EEG Signal Generator.
    Author: Wickramaratne SD, Parekh A.
    Journal: Annu Int Conf IEEE Eng Med Biol Soc; 2023 Jul; 2023():1-4. PubMed ID: 38083563.
    Abstract:
    Synthetic data generation has become increasingly popular with the increasing use of generative networks. Recently, Generative Adversarial Network (GAN) architectures have produced exceptional results in synthetic image generation. However, time series generation still needs to be studied. This paper proposes a Conditional GAN-based system to generate unique samples of non-REM sleep electroencephalographic (EEG) signals. The CGAN model had a 1-D Convolution Neural Network based architecture. The model was trained using real EEG from healthy controls. The trained model can generate an artificial 30-second epoch of non-REM sleep whose power spectrum is identical to that of a real sleep EEG.Clinical relevance- Sleep EEG simulation can be used to train and enhance the skillset of fellows and technicians in the sleep medicine field. Variations in EEG signals can be highly complex to model mathematically; however, here, we harness the power of deep learning, using generative models such as CGANs to train, model complex data distributions, and generate diverse and artificial but realistic EEG signals during non-REM sleep.
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