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Title: [Discovery of hemoglobin J Baltimore in an episode of methemoglobinemia in an infant]. Author: Mailfert R, North ML, Duwig I, Galacteros F, Fischer D, Mayer S. Journal: Nouv Rev Fr Hematol (1978); 1986; 28(5):315-20. PubMed ID: 3808941. Abstract: A case of a heterozygote for Hb J Baltimore is reported in a French family. This variant hemoglobin was coincidentally discovered during an episode of methemoglobinemia in a 6-week-old baby. The father and one of the brothers were also carriers of the trait. Hematological findings for all of them were normal. As Hb J Baltimore is a frequently occurring hemoglobin variant, we discuss: its possible role in the appearance of methemoglobin, and whether this mutation in different racial groups (Caucasians of West Europe, Canadians, and American blacks) has a common origin or more probably arises from a number of independent mutations.[Abstract] [Full Text] [Related] [New Search]