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  • Title: Effects of nasopharyngeal cocaine or pharyngeal benzocaine on esophageal motility.
    Author: Hacker JF, Cattau EL.
    Journal: Am J Gastroenterol; 1987 Feb; 82(2):127-9. PubMed ID: 3812417.
    Abstract:
    The esophageal effect of topical anesthetics applied to the nasopharynx was evaluated. Eight healthy volunteers underwent an esophageal motility study after each of the following: no anesthesia, 5% cocaine solution applied to the nasopharynx, and 20% benzocaine spray applied to the pharynx. Upper esophageal sphincter relaxation was prolonged after use of the 5% cocaine solution. No other significant effects on esophageal motility or pressures were noted.
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