These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: An ICT-switched fluorescent probe for visualizing lipid and HClO in lipid droplets during ferroptosis.
    Author: Yao L, Song H, Yin C, Huo F.
    Journal: Chem Commun (Camb); 2024 Jan 18; 60(7):835-838. PubMed ID: 38131382.
    Abstract:
    Herein, we have designed and synthesized a fluorescent probe, LDs-ClO, which can detect hypochlorous acid and lipid accumulation simultaneously in lipid droplets of live RAW 264.7 cells. Cell ferroptosis was discovered to lead to an increase in HClO levels, and to possibly further stimulate accumulation of lipid. We expect the results of this work with LDs-ClO to promote the study of physiological and pathological processes related to lipid droplets and hypochlorite.
    [Abstract] [Full Text] [Related] [New Search]