These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Plasma levels of clomipramine and declomipramine in patients with depression: a study of its correlation with therapeutic efficacy].
    Author: Wargny E, Lamiable D, Havet JM, Denis J, Millart H, Choisy H, Pascalis G.
    Journal: Ann Med Psychol (Paris); 1986 Apr; 144(4):396-406. PubMed ID: 3813333.
    Abstract:
    Twenty four in-patients with an endogenous or non endogenous depressive syndrome (9 and 15, respectively) were treated in hospital for 21 days with various dosages regimens of clomipramine. Plasma concentrations of clomipramine and demethylclomipramine were determined once a week in blood samples. Therapeutic effects were assessed with Hamilton Rating Scale. At day 21, optimal therapeutic effect was observed when the sum of clomipramine and demethylclomipramine plasma levels was situated between 200-400 ng/ml.
    [Abstract] [Full Text] [Related] [New Search]