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  • Title: Hydroxyurea reduces infections in children with sickle cell anemia in Uganda.
    Author: Namazzi R, Bond C, Conroy AL, Datta D, Tagoola A, Goings MJ, Jang JH, Ware RE, Opoka R, John CC.
    Journal: Blood; 2024 Apr 04; 143(14):1425-1428. PubMed ID: 38169476.
    Abstract:
    After starting hydroxyurea treatment, Ugandan children with sickle cell anemia had 60% fewer severe or invasive infections, including malaria, bacteremia, respiratory tract infections, and gastroenteritis, than before starting hydroxyurea treatment (incidence rate ratio, 0.40 [95% confidence interval, 0.29-0.54]; P < .001).
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