These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Influence of bigumal on the blood coagulation system and on the anticoagulant effect of heparin].
    Author: kremneva VF, Ushkalova EA, Shcheglova NV.
    Journal: Farmakol Toksikol; 1986; 49(6):43-5. PubMed ID: 3817142.
    Abstract:
    It was found that in the blood plasma bigumal even at high dose (15 mg/kg) exerted no effect on the parameters of partial thromboplastin and thrombin time but increased the blood plasma tolerance to heparin. Both in buffer medium and blood plasma bigumal effectively decreased the specific effect of heparin. Oral acute (5 mg/kg) and long-term (3 mg/kg daily for 5 days) administration of bigumal to rabbits decreased the time of whole blood coagulation, partial thromboplastin time and reduced the sensitivity of animals to heparin.
    [Abstract] [Full Text] [Related] [New Search]