These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Tn10 mediated integration of the plasmid R100.1 into the bacterial chromosome: inverse transposition.
    Author: Chandler M, Roulet E, Silver L, Boy de la Tour E, Caro L.
    Journal: Mol Gen Genet; 1979 May 23; 173(1):23-30. PubMed ID: 381840.
    Abstract:
    Upon integration into the bacterial chromosome the drug resistance plasmid R100.1 often loses its tetracycline resistance character. We have analyzed an Hfr strain formed by such an integration and an R-prime plasmid derived from it. We find that integration took place within the Tn10 transposon, that the two IS10 sequences were retained, but that at least 80% of the transposon segment located between them, and carrying the tetracycline resistance genes, had been lost. We suggest that integration of R100.1 was mediated by an inverse transposition using the IS10 sequences.
    [Abstract] [Full Text] [Related] [New Search]