These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis and antitumor activity of N-terminal proline-containing peptide-(chloroethyl)nitrosoureas.
    Author: Süli-Vargha H, Jeney A, Lapis K, Medzihradszky K.
    Journal: J Med Chem; 1987 Mar; 30(3):583-6. PubMed ID: 3820230.
    Abstract:
    The N alpha-(2-chloroethyl)-N-nitrosocarbamoyl derivatives of H-Pro-Lys(X)-Pro-Val-NH2 (X: tert-butyloxycarbonyl, formyl, (2-chloroethyl)nitrosocarbamoyl) were synthesized. It was found that the bis-substitution of the urea N3 in these derivatives does not decrease the antitumor activity influenced mainly by the nature of the carrier molecule as a whole.
    [Abstract] [Full Text] [Related] [New Search]