These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Mutagenicity of 4-hydroxynonenal in V79 Chinese hamster cells.
    Author: Cajelli E, Ferraris A, Brambilla G.
    Journal: Mutat Res; 1987 Feb; 190(2):169-71. PubMed ID: 3821775.
    Abstract:
    4-Hydroxynonenal (HNE), a major product of the peroxidation of liver microsomal lipids, was examined for mutagenic activity at the hypoxanthine-guanine phosphoribosyltransferase locus in V79 Chinese hamster lung cells. At concentrations ranging from 10 to 45 microM, HNE induced a dose-dependent increase in the number of mutations to 6-thioguanine resistance, which reached the level of 4.7X baseline at the highest concentration tested.
    [Abstract] [Full Text] [Related] [New Search]