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  • Title: PS-5, a new beta-lactam antibiotic. II. Antimicrobial activity.
    Author: Sakamoto M, Iguchi H, Okamura K, Hori S, Fukagawa Y, Ishikura T, Lein J.
    Journal: J Antibiot (Tokyo); 1979 Apr; 32(4):272-9. PubMed ID: 38238.
    Abstract:
    PS-5, a new beta-lactam antibiotic, has relatively potent antimicrobial activity against Gram-positive and Gram-negative bacteria, especially the Enterobacter groups, Serratia marcescens, the Proteus groups and Klebsiella pneumoniae. The activity of PS-5 against many beta-lactamase-producing organisms is greater than that of cefoxitin or cefazolin. PS-5 has good therapeutic activity in mice infected with Staphylococcus aureus Smith or Enterobacter cloacae 45.
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