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  • Title: [Evaluation of the effect of obsidan in essential hypertension patients with different types of circulation].
    Author: Goloshchapov OA, Pribylova NN, Kotova LN, Nozhnova LP.
    Journal: Ter Arkh; 1986; 58(11):29-32. PubMed ID: 3824185.
    Abstract:
    A study of the effect of propranolol on the central hemodynamics using the polycardiographic method in 90 patients with essential hypertension showed that in 83% of them, disregarding the type of hemodynamics, beta-blocker made a negative chronotropic effect, and in 17% of the patients it increased the heart rate. In the patients with the hyperkinetic circulation the negative inotropic effect of propranolol was noted in 42% of the cases, and in the patients with the eu- and hypokinetic circulation 37.5%. However, the improvement of myocardial contractility expressed in an increase in the cardiac and stroke blood volume, the stroke and cardiac indices, and a decrease in peripheral vascular resistance were found in 24.4% of the total number of patients.
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