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  • Title: Early detection of streptococcal group antigens in skin samples by latex particle agglutination.
    Author: Bernard P, Toty L, Mounier M, Denis F, Bonnetblanc JM.
    Journal: Arch Dermatol; 1987 Apr; 123(4):468-70. PubMed ID: 3827278.
    Abstract:
    The streptococcal group antigens (A to G) were researched in skin biopsy specimens by a latex agglutination technique using commercial (Slidex Streptokit bio-Mérieux and Streptex Wellcome) and experimental reagents. Twenty-seven patients with obvious cutaneous infections (12 cases of erysipelas, nine cases of cellulitis, and six cases of necrotizing fasciitis) and 27 age- and sex-matched controls were studied. Our preliminary data demonstrated the possibility of an early diagnosis of streptococcal cutaneous infections involving the deep dermis and/or hypodermis. We used a latex agglutination technique that is quite specific and gives a better sensitivity (0.63) than either conventional bacteriologic cultures on needle aspiration or skin biopsy specimens.
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