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  • Title: Biphasic endotoxin fever in the newborn rabbit.
    Author: Székely M.
    Journal: Acta Physiol Acad Sci Hung; 1978; 51(4):389-92. PubMed ID: 382742.
    Abstract:
    Rabbits aged 6-10 days responded to 20 or 50 microgram/kg i. p. or i. v. E. coli endotoxin with characteristic biphasic fever, whereas 0-3-day-old rabbits reacted with monophasic fever which coincided with the first-phase rise of the older group. In the rabbit, the mechanisms responsible for the first-phase and the second-phase febrile temperature rises appear separately in ontogenesis in the first week of extrauterine life.
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