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Title: Upper extremity functional rating for patients with Duchenne muscular dystrophy. Author: Lord JP, Portwood MM, Lieberman JS, Fowler WM, Berck P. Journal: Arch Phys Med Rehabil; 1987 Mar; 68(3):151-4. PubMed ID: 3827555. Abstract: The corresponding deterioration of upper extremity strength and functional capability with increasing age and the relationship between average strength and function were evaluated in 28 boys with Duchenne muscular dystrophy (DMD). Manual muscle testing (MMT) was used to evaluate strength and the Brooke upper extremity grading scale to rate upper extremity function. Mean MMT was found to relate to age in logarithmic fastion, ie, a 1% increase in age led to a 0.9% decrease in mean MMT. Functional grade (FG) related to age in a more complex fashion, revealing three groups based on age: under age 10, all in FG 1; between ages 10 and 13, concentration in FG 2 through 4; and over age 13, eight of ten in FG 5. Regression analysis did not contribute further useful information. Finally, mean MMT was found to be highly significantly related to FG. The plot of mean MMT against FG revealed an S-shaped curve, with rapidly rising functional grade once an average upper extremity strength of 4w was reached. The Brooke scale appears to be useful in describing upper extremity function among DMD patients, although it may reflect a three-grade rather than a six-grade discrimination capability. In describing the natural history of DMD, this scale demonstrates a pattern of rapid functional deterioration during the early adolescent years. This functional deterioration apparently takes place when the decline in strength reaches a threshold which cannot be compensated by muscle substitutions. At that time function deteriorates along a relatively rapid but undefined course.[Abstract] [Full Text] [Related] [New Search]