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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Failure of metoclopramide to control emesis or nausea due to stressful angular or linear acceleration.
    Author: Kohl RL.
    Journal: Aviat Space Environ Med; 1987 Feb; 58(2):125-31. PubMed ID: 3827787.
    Abstract:
    Orally administered metoclopramide (REGLAN) at doses of 10 or 20 mg, 75 min prior to either stressful linear acceleration (parabolic flight) or cross-coupled accelerative semicircular canal stimulation in a rotating chair was evaluated for its ability to prevent emesis or nausea II, respectively. Although metoclopramide is an effective antiemetic agent that enhances gastric emptying and prevents cancer chemotherapy-induced emesis, we were unable to demonstrate any significant (p less than 0.05) effects of this drug on motion sickness.
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