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  • Title: [Clinical trial of aztreonam in the field of obstetrics and gynecology].
    Author: Tateno M, Maruyama C.
    Journal: Jpn J Antibiot; 1985 Dec; 38(12):3599-605. PubMed ID: 3834144.
    Abstract:
    Clinical effect and safety of aztreonam (AZT) in the obstetrics and gynecology were studied in 17 cases of obstetric and gynecological infections. AZT was administered at a dose of 2 g per day by intravenous drip infusion, for 4-8 days depending on severity of the disease. The results showed that AZT was effective in 14 out of 17 cases and the overall efficacy rate was 82.4%. E. coli, Enterobacter, E. faecalis, etc. were detected in 8 out of 17 cases, and after AZT treatment other strains appeared in 3 clinically effective cases. There was a slight elevation of GOT and GPT in 1 case but no other appreciable side effect or abnormal laboratory value was observed.
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