These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Action of cobra venom phospholipase A2 on large unilamellar vesicles: comparison with small unilamellar vesicles and multibilayers.
    Author: Kensil CR, Dennis EA.
    Journal: Lipids; 1985 Feb; 20(2):80-3. PubMed ID: 3838567.
    Abstract:
    Phospholipase A2 (Naja naja naja) catalyzes the hydrolysis of dipalmitoyl phosphatidylcholine in small unilamellar vesicles (SUVs) with a faster initial rate than in large unilamellar vesicles (LUVs) and multilamellar vesicles (MLVs). For the SUVs, the hydrolysis was initially faster for gel phase than liquid crystalline phase phospholipid. For both LUVs and MLVs, hydrolysis was low except in a small temperature range around the thermotropic phase transition of the phospholipid. In this temperature range, the reaction time course of phospholipase action on dipalmitoyl phosphatidylcholine in LUVs and MLVs included a lag period. With SUVs, a lag period also was observed above the phase transition temperature, but it was not observed below it.
    [Abstract] [Full Text] [Related] [New Search]