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  • Title: [Block of NK cell activity by ICO-11 monoclonal antibodies].
    Author: Baryshnikov AIu, Trubcheninova LP, Savel'eva EV, Tupitsyn NN, Frenkel' MA.
    Journal: Eksp Onkol; 1985; 7(3):34-6. PubMed ID: 3839452.
    Abstract:
    Antigen expression determined by ICO-11 monoclonal antibodies was studied on leukemia cells from bone marrow, blood cells from patients with lymphoproliferative diseases and natural killer (NK) cells responsible for natural resistance. ICO-11 monoclonal antibodies were shown to recognize the antigen expressed on NK-cells, predecessors of T-cells (thymocytes), myelomonocytes (myeloblasts, monoblasts) and to block NK-cell activity.
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