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  • Title: Sucralfate compared with ranitidine in the short-term healing of duodenal ulcers.
    Author: Lam KT, Lai ST, Kan YS, Chan AY.
    Journal: J Int Med Res; 1985; 13(6):338-41. PubMed ID: 3841079.
    Abstract:
    The efficacy of sucralfate (1 g four times daily) and ranitidine (150 mg twice daily) in the short-term healing of duodenal ulcers has been assessed in a randomized single-blind trial involving 104 patients with three drop-outs. The healing rate at 3 weeks of 83% for sucralfate and 84% for ranitidine improved to 96% and 92%, respectively, at 6 weeks. The difference between the two treatment groups was not statistically significant. Smoking and male sex had no influence on the healing rates. Constipation was a prominent symptom in sucralfate treatment which was otherwise a safe and effective therapy.
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