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Title: PD 118,576: a new antitumor macrolide antibiotic. Author: Wilton JH, Hokanson GC, French JC. Journal: J Antibiot (Tokyo); 1985 Nov; 38(11):1449-52. PubMed ID: 3841121. Abstract: The isolation and properties of PD 118,576, a new cytotoxic antibiotic obtained from the culture broth of a Streptomyces sp., are described. The structure of this compound was established by spectral analyses of the parent compound and its tri-O-acetyl derivative. PD 118,576 proved to be related to the bafilomycins and therefore is a new member of this recently discovered family of macrolide antibiotics.[Abstract] [Full Text] [Related] [New Search]