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  • Title: Stereoselective bioaccumulation and degradation of chiral pesticide hexythiazox in earthworm-soil microcosm.
    Author: Song N, Zhuang J, Zhang H, Qian M, Wu H, Sun N.
    Journal: Ecotoxicol Environ Saf; 2024 Mar 15; 273():116148. PubMed ID: 38422791.
    Abstract:
    The chiral pesticide hexythiazox was extensively employed in agricultural activities and has garnered growing concern for its harmful impact on the ecosystem. This study investigates the toxicodynamic earthworm at the enantiomeric level of hexythiazox. Earthworms exhibited notable enantioselectivity during the accumulation stage. Furthermore, the presence of earthworms can impact the rate of degradation and enantioselectivity of hexythiazox in soil. The accumulation of the two hexythiazox enantiomers in the earthworm adhered to the one-compartment model, whereas the elimination phase was governed by the first-order kinetics equation. Furthermore, it was discovered that there was no notable enantioselectivity observed during the elimination phase.
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