These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Methodology for the testing of food dyes for genotoxic activity: experiments with red 2G (C.I. 18050).
    Author: Haveland-Smith RB, Combes RD, Bridges BA.
    Journal: Mutat Res; 1979 Aug; 64(4):241-8. PubMed ID: 384228.
    Abstract:
    A methodology for investigating genotoxicity of food colours using the fluctuation and DNA-repair assays with bacteria is described. In addition, a liquid repair test, developed to permit incorporation of microsomes and the quantitative estimation of cell viability, has been characterised with a number of positive control agents. Results obtained in these systems suggest that the food colour Red 2G induces repairable DNA damage and base-substitution mutation, but only in the presence of a rat-liver microsomal preparation. The significance of the data in the light of other toxicological information is discussed.
    [Abstract] [Full Text] [Related] [New Search]