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  • Title: Case Report: Clinical and Pathological Findings of Tuberculous Gumma: A Case Report and Literature Review.
    Author: Deng LJ, Ye Q, Luo SY, Wang QX, Fang S.
    Journal: Am J Trop Med Hyg; 2024 Apr 03; 110(4):805-808. PubMed ID: 38471180.
    Abstract:
    Tuberculous gumma (TG) is a rare type of cutaneous tuberculosis thought to occur as a result of the hematogenous spread of Mycobacterium tuberculosis, which is more common in immunosuppressed individuals. An 8-year-old boy presented with a 2-month history of multiple indolent enlarging ulcerated nodules on his left upper extremity. He had a past medical history of bacille Calmette-Guerin vaccine induced lupus vulgaris. Skin biopsy of the nodules showed granulomas and neutrophil-dominated purulent inflammation. Ziehl-Neelsen staining was negative, and the cultures were positive for M. tuberculosis. Furthermore, the M. tuberculosis complex was identified using metagenomic next-generation sequencing. Standard antitubercular therapy was started at full doses, and the skin lesions had significantly improved 3 months later. Here we review the literature since 2000 and describe the clinical and pathological features of TG.
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