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  • Title: Excelxylin A: a new seco A-ring tirucallane triterpenoid from the stem bark of Dysoxylum excelsum.
    Author: Kautsari A, Naini AA, Mayanti T, Nurlelasari, Harneti D, Farabi K, Maharani R, Harizon, Azmi MN, Supratman U.
    Journal: J Asian Nat Prod Res; 2024 Jul; 26(7):843-849. PubMed ID: 38511479.
    Abstract:
    A new seco-A tirucallane triterpenoid named excelxylin A (1), along with two known seco-A triterpenoids (2-3), were isolated from the n-hexane extract of Dysoxylum excelsum (Spreng.) Blume ex G.Don stem bark. The structure and stereochemistry configuration of compounds 1-3 was established by NMR, IR, and HR-ESI-MS spectroscopic data analyses and comparison of their NMR data with literatures. The compounds exhibited the carbon framework for seco-A ring tirucallane triterpenoid, first reported in the Dysoxylum genus. All compounds were tested for their cytotoxicity against human cervical HeLa cells.
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