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  • Title: Injectable depot corticosteroid therapy in hay fever.
    Author: Kronholm A.
    Journal: J Int Med Res; 1979; 7(4):314-7. PubMed ID: 385402.
    Abstract:
    Forty-two patients with stable hay fever were treated with injections of long-acting corticosteroids. They were randomly assigned to either 2 ml of betamethasone dipropionate + betamethasone phosphate (Diprospan) or 2 ml of methylprednisolone acetate (Depomedrol). Eye and nose symptoms were evaluated according to a four-step scale of weekly intervals. Both steroids were highly efficacious in reducing the symptoms with maximal effect one week after injection and slow diminution during subsequent weeks. However, Diprospan showed a significantly better effect than Depomedrol on all symptoms. It is concluded that depot injectable formulations of corticosteroids are a useful therapeutical alternative in hay fever.
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