These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of molybdenum and tungsten on mammary carcinogenesis in SD rats.
    Author: Wei HJ, Luo XM, Yang SP.
    Journal: J Natl Cancer Inst; 1985 Feb; 74(2):469-73. PubMed ID: 3856053.
    Abstract:
    Virgin female rats of the SD strain were fed ad libitum a nutritionally adequate semipurified diet and demineralized water (groups 1 and 2), or the same diet with 10 ppm molybdenum (group 3) or 150 ppm tungsten (group 4) added to the drinking water. The animals in groups 2-4 received a single iv injection of 5 mg N-nitroso-N-methylurea (NMU; CAS: 684-93-5)/100 g body weight at 50 days of age. One hundred and twenty-five days after the NMU treatment, group 2 exhibited a 50.0% incidence of mammary carcinoma. Group 4 exhibited a significant increase in carcinoma incidence (79.2%) and the value for group 3 (45.5%) was not significantly different from that of group 2. The carcinoma incidence of group 3 (50.0%) was significantly lower than that of group 2 (90.5%) or group 4 (95.7%) 198 days after NMU treatment.
    [Abstract] [Full Text] [Related] [New Search]