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  • Title: [Use of aerosils in activating plasma prekallikrein].
    Author: Veremeenko KN, Pogorelaia NF.
    Journal: Vopr Med Khim; 1979; 25(4):375-9. PubMed ID: 38571.
    Abstract:
    Activation of prekallikreine from human blood plasma was studied using silica (airsiles), which carried functional groups with acidic and alkaline properties on the surface. Prekallikrein was similarly activated by amino- and carboxyairsiles, possessing positive and negative electric charges, respectively, at neutral pH value in a medium. Lysozyme, ribonuclease and spermidine inhibited partially the prekallikreine activation; spermine inhibited it completely.
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