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Title: Synchronization of rapid globin expression in murine erythroleukemic cells. Author: Zucker RM. Journal: Res Commun Chem Pathol Pharmacol; 1985 Feb; 47(2):301-4. PubMed ID: 3857701. Abstract: The addition of butyric acid (BA) to murine erythroleukemia cells (MELC) produces the expression of primarily A and E2 hemoglobins while DMSO incubation produces the expression of primarily A hemoglobin. Preincubation of MELC with DMSO followed by BA induction accelerates the expression of hemoglobins in a synchronous manner, yielding the preferential synthesis of alpha and y globins, and E2 hemoglobin.[Abstract] [Full Text] [Related] [New Search]