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  • Title: [Mathematical model of the sarcomagenic action of osteotropic alpha emitters].
    Author: Petoian IM, Filiushkin IV.
    Journal: Radiobiologiia; 1985; 25(3):356-61. PubMed ID: 3860888.
    Abstract:
    A model for osteosarcoma induction by alpha-emitters is proposed which is based on a well-known conception on the mechanisms of radiation-induced cancer, the processes of bone tissue regeneration, and the kinetics of cells subjected to carcinogenic risk. The main mathematical relations of the proposed model are presented. The dose-effect relationship of the model is compared with the epidemiological data available on the development of osteosarcoma in patients affected by long-lived radium isotopes.
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