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  • Title: Effect of a megadose of ascorbic acid, a meal and orange juice on the absorption of selenium as sodium selenite.
    Author: Robinson MF, Thomson CD, Huemmer PK.
    Journal: N Z Med J; 1985 Aug 14; 98(784):627-9. PubMed ID: 3861972.
    Abstract:
    Urinary and faecal excretions of selenium were measured for five days following a dose of 1 mg Se as sodium selenite in ten young women after an overnight fast. The selenite was taken two hours before a meal or mixed with 1 g ascorbic acid; or with a continental type breakfast providing 4.5-5.6 micrograms Se and 0.6-0.8 mg Cu, with or without 200 ml orange juice (60 mg ascorbic acid). The light meal appeared to have little effect on selenite-Se absorption, and orange juice appeared even to assist it. But the availability of Se was reduced almost to zero when selenite and 1 g ascorbic acid were taken together well before the meal.
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