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  • Title: Diffuse mandibular enlargement.
    Author: Ellis GL, Connole PW.
    Journal: J Am Dent Assoc; 1985 Oct; 111(4):630-2. PubMed ID: 3863864.
    Abstract:
    Paget's disease of the jaw has the following characteristics: slow progression of jaw enlargement; bilateral jaw involvement; often polyostotic, but not generalized skeletal disease; diffuse, irregular radiopaque areas of the jaw; elevated serum alkaline phosphatase level; and a biopsy specimen showing thick, irregular bone trabeculae with a mosaic pattern of reversal lines and numerous osteoblasts and osteoclasts in a fibrovascular stroma. Management of a patient with Paget's disease of bone usually is carried out by treating the symptoms of the disease as they arise. Bone can be removed for esthetic reasons when needed.
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