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  • Title: [Clinical studies of ceftizoxime suppositories in the pediatric field].
    Author: Sunakawa K, Hirota A, Saito N, Ishizuka Y.
    Journal: Jpn J Antibiot; 1985 Oct; 38(10):2889-95. PubMed ID: 3866082.
    Abstract:
    Ceftizoxime suppository (CZX-S) was given to 19 children with infections, including upper and lower respiratory tract infections, urinary tract infections and otitis media at dose level of 18-83 mg/kg/day divided into 2-3 times. Clinical response was excellent in 12 patients, good in 6 patients and poor in 1 patient. Bacteriological response was eradicated in 11 strains, decreased in 3 strains and unchanged in 4 strains. No severe side effects were observed with this drug. These results obtained suggest that CZX-S should be a useful antibiotic in treatment of infections in pediatric field.
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