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  • Title: Comparative Analysis of Crosslinking Methods and Their Impact on the Physicochemical Properties of SA/PVA Hydrogels.
    Author: Niewiadomski K, Szopa D, Pstrowska K, Wróbel P, Witek-Krowiak A.
    Journal: Materials (Basel); 2024 Apr 15; 17(8):. PubMed ID: 38673173.
    Abstract:
    Hydrogels, versatile materials used in various applications such as medicine, possess properties crucial for their specific applications, significantly influenced by their preparation methods. This study synthesized 18 different types of hydrogels using sodium alginate (SA) and two molecular weights of polyvinyl alcohol (PVA). Crosslinking agents such as aqueous solutions of calcium (Ca2+) and copper (Cu2+) ions and solutions of these ions in boric acid were utilized. The hydrogels were subjected to compression strength tests and drying kinetics analysis. Additionally, six hydrogel variants containing larger PVA particles underwent Fourier-transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA) post-drying. Some samples were lyophilized, and their surface morphology was examined using scanning electron microscopy (SEM). The results indicate that the choice of crosslinking method significantly impacts the physicochemical properties of the hydrogels. Crosslinking in solutions with higher concentrations of crosslinking ions enhanced mechanical properties and thermal stability. Conversely, using copper ions instead of calcium resulted in slower drying kinetics and reduced thermal stability. Notably, employing boric acid as a crosslinking agent for hydrogels containing heavier PVA molecules led to considerable improvements in mechanical properties and thermal stability.
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