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  • Title: Red blood cell membrane lipid peroxidation and chronic haemolysis in haemodialysis patients.
    Author: Taccone-Gallucci M, Lubrano R, Mazzarella V, Bandino D, Meloni C, Morosetti M, Elli M, Giardini O, Boffo V, Tozzo C.
    Journal: Life Support Syst; 1985; 3 Suppl 1():41-4. PubMed ID: 3870599.
    Abstract:
    Pre dialysis concentrations of malonyldialdehyde (MDA) in the red blood cell membranes and pre and post dialysis percent variation of plasma haemoglobin levels are studied in a group of uraemic patients on maintenance haemodialysis both before and after a therapeutic trial with vitamin E. The findings show a significant correlation between MDA levels and percent variation of plasma haemoglobin during dialysis, thus indicating that reducing the amount of lipid peroxidation can help to reduce intradialytic chronic haemolysis.
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