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Pubmed for Handhelds

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  • Title: A double-blind trial of single-dose chemoprophylaxis with co-trimoxazole during vaginal hysterectomy and repair.
    Author: Mathews DD, Agarwal V, Gordon AM, Cooper J.
    Journal: Br J Obstet Gynaecol; 1979 Sep; 86(9):737-40. PubMed ID: 387070.
    Abstract:
    Twenty-five patients received 10 ml co-trimoxazole (800 mg sulphamethoxazole and 160 mg trimethoprim) and 25 a placebo by intravenous infusion during one hour from the commencement of surgery for vaginal hysterectomy with anterior colporrhaphy and posterior colpo-perineorrhaphy. Single-dose chemoprophylaxis with co-trimoxazole was shown to be effective in reducing the incidence of postoperative febrile morbidity and urinary tract infection, especially that caused by Proteus species.
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