These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effect of sensitization of pregnant Lewis rats with encephalitogen on the subsequent susceptibility of their offspring to allergic encephalomyelitis.
    Author: Mertin LA, Sljivic V, Rumjanek VM.
    Journal: Immunology; 1985 Feb; 54(2):381-8. PubMed ID: 3871422.
    Abstract:
    In a previous report (Smith & Rumjanek, 1984), it was shown that offspring of female Lewis rats which had been sensitized with encephalitogen during the second, but not the third or first, week of pregnancy, were resistant to the induction of EAE at 10 weeks of age. These observations have been extended to show that transfer of protection, from mothers to offspring, occurs during lactation. It is shown, furthermore, that sensitization leads to decreased incidence of disease in offspring, maternal clinical status simply determining the duration of protection enjoyed by offspring. The possible source of this protection is discussed.
    [Abstract] [Full Text] [Related] [New Search]