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  • Title: IgA containing circulating immune complexes and IgA anti-single stranded DNA antibodies in patients with obstructive jaundice.
    Author: Ohshio G, Furukawa F, Sekita K, Manabe T, Tobe T, Hamashima Y.
    Journal: Clin Exp Immunol; 1985 Feb; 59(2):435-41. PubMed ID: 3872190.
    Abstract:
    Elevated levels of IgA containing circulating immune complexes (IgA-CIC) and IgG containing (IgG-) CIC were detected in patients with obstructive jaundice due to biliary tract stones and/or tumour of biliary tract or pancreas. Levels of serum IgA were also elevated, and correlated with the levels of IgA-CIC. The levels of IgA and IgG anti-single stranded (ss) DNA were elevated, and there was a significant correlation between the levels of IgA-CIC and IgA anti-ssDNA antibodies. The cause of IgA-CIC increase in patients with obstructive jaundice might be due not only to simple obstruction of biliary tract but also to other factors such as a tissue destruction.
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